•Why it earns a slot
Why it earns a slot: it is the novel that got its author prosecuted for obscenity and still defined literary realism, refusing every romantic convention by letting its heroine's appetite for a bigger life get her killed by her own hand while the fools around her prosper.
A doctor's wife burns through two lovers and a mountain of debt chasing a romance the provinces can't supply, then lies her way into the pharmacist's poison closet and eats arsenic straight from the jar with her bare hand.
This distillation is written from the freely available original, which is always the better read when you have the time: Project Gutenberg.