•Why it earns a slot
Why it earns a slot: it is the text that first drew the line between what is and what ought to be, and every argument about facts versus values since has had to answer to it.
Hume tries to build a complete science of the mind on experience alone, and ends up proving that reason cannot justify cause, self, or morality without help from feeling.
This distillation is written from the freely available original, which is always the better read when you have the time: Project Gutenberg.